MPS VII is one of the rarest types of mucopolysaccharidosis

Mucopolysaccharidosis VII (MPS VII), also called Sly syndrome, is a genetic metabolic disorder caused by a deficiency of the lysosomal enzyme β–glucuronidase.

β–glucuronidase is an enzyme that helps break down glycosaminoglycans (GAGs). The inability to properly break down GAGs leads to a progressive accumulation in many tissues and results in a multi-system disease.1-3

For Health Care Professionals

CLINICAL TRIALS

Learn about clinical trials in adult and pediatric patients with MPS VII

ENZYME DEFICIENCY TESTING

No-cost enzyme deficiency testing is available for patients with MPS VII symptoms or non-immune hydrops fetalis

HYDROPS & MPS VII CORRELATION

Understand non-immune hydrops fetalis and MPS VII

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References: 1. National Institutes of Health. Mucopolysaccharidosis type VII. http://ghr.nlm.nih.gov/condition/mucopolysaccharidosis-type-vii. Reviewed August 2010. Published July 13, 2015. 2. Society for Mucopolysaccharide Diseases. Guide to Understanding Mucopolysaccharidosis VII (MPS VII) Sly. 3. Data on file. Ultragenyx Pharmaceutical Inc.